SCHEMBL31748716

SCHEMBL31748716

COc1ccccc1C(=O)Nc1ccc2nc(-c3cccnc3)[nH]c2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.68
▸ HPGD P15428 2/20 0.68
▸ HSD17B10 Q99714 1/20 0.68
▸ POLB P06746 2/20 0.64
▸ MAPT P10636 2/20 0.64
▸ LMNA P02545 1/20 0.64
▸ TP53 P04637 4/20 0.63
▸ RECQL P46063 1/20 0.63
▸ L3MBTL1 Q9Y468 1/20 0.63
▸ GFER P55789 1/20 0.62
▸ HPSE Q9Y251 1/20 0.61
▸ KDM4E B2RXH2 2/20 0.58
▸ ABL1 P00519 2/20 0.58
▸ PDGFRB P09619 2/20 0.58
▸ BCR P11274 2/20 0.58
▸ PDGFRA P16234 2/20 0.58
▸ PRKCA P17252 2/20 0.58
▸ EGFR P00533 1/20 0.58
▸ NR2E3 Q9Y5X4 4/20 0.56
▸ KMT2A Q03164 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26597195 1.00 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL30667673 1.00 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL26753795 0.86 ALDH1A1 (0.70) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL31748608 0.85 NR2E3 (0.63) ALDH1A1HPGDHSD17B10MAPTLMNA
SCHEMBL26597196 0.85 NR2E3 (0.63) ALDH1A1HPGDHSD17B10MAPTLMNA
SCHEMBL31748600 0.85 NR2E3 (0.62) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL26597175 0.85 NR2E3 (0.62) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL31748765 0.83 MAPT (0.82) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL30667683 0.83 MAPT (0.82) ALDH1A1HPGDHSD17B10POLBMAPT
SCHEMBL26597186 0.83 MAPT (0.82) ALDH1A1HPGDHSD17B10POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, CCR10, IL2 ALDH1A1 4052/4885HPGD 2230/4885HSD17B10 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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