Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2977669 | 0.89 | TAS2R14 (0.32) | TSHRLMNAGAATAS2R14 | |
| Trifluoroacetic Acid SCHEMBL2967136 | 0.88 | TAS2R14 (0.32) | TSHRLMNAGAATAS2R14 | |
| Trifluoroacetic Acid SCHEMBL2660748 | 0.86 | TAS2R14 (0.31) | TAS2R14 | |
| Trifluoroacetic Acid SCHEMBL2970815 | 0.85 | TAS2R14 (0.34) | TSHRLMNAGAATAS2R14ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2660751 | 0.83 | F2 (0.33) | TAS2R14ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2660008 | 0.83 | TAS2R14 (0.31) | TAS2R14 | |
| Trifluoroacetic Acid SCHEMBL2977946 | 0.83 | HTR1D (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL2978479 | 0.83 | ALDH1A1 (0.33) | TAS2R14ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2660750 | 0.82 | TAS2R14 (0.32) | TAS2R14 | |
| SCHEMBL2668756 | 0.82 | TSHR (0.32) | TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |