Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26599235 | 0.83 | KMT2A (0.70) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL11887813 | 0.82 | KMT2A (1.00) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL11334426 | 0.77 | KMT2A (0.61) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL11385461 | 0.76 | ALDH1A1 (0.77) | KMT2ASMN1; SMN2BRD4KDM4EHPGD | |
| SCHEMBL11332441 | 0.75 | KMT2A (0.58) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL3733227 | 0.73 | KMT2A (0.61) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL22717633 | 0.72 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL3904820 | 0.72 | ALDH1A1 (0.48) | KMT2ASMN1; SMN2BRD4KDM4ERAB9A | |
| SCHEMBL34467571 | 0.71 | ADRB2 (0.41) | KMT2ASMN1; SMN2KDM4ERAB9ANPC1 | |
| Methylamine SCHEMBL6499701 | 0.70 | ADRB2 (0.64) | BRD4HPGDLMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202623-A1 | POLQ INHIBITOR COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2023-10-26 | — | — | WO | disclosed |