Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967711 | 0.82 | ATM (0.69) | ATMALDH1A1POLBGLSMEN1 | |
| SCHEMBL17967124 | 0.82 | ALDH1A1 (0.72) | ATMALDH1A1POLBSMN1; SMN2GLS | |
| SCHEMBL3729367 | 0.81 | ATM (1.00) | ATMALDH1A1POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21391938 | 0.81 | ATM (0.67) | ATMALDH1A1POLBGLSMEN1 | |
| SCHEMBL18010484 | 0.78 | ALDH1A1 (0.75) | ATMALDH1A1POLBNPC1RAB9A | |
| SCHEMBL19793294 | 0.78 | ATM (0.63) | ATMALDH1A1POLBGLSMEN1 | |
| SCHEMBL26599691 | 0.78 | ATM (0.63) | ATMALDH1A1POLBGLSMEN1 | |
| SCHEMBL10873457 | 0.71 | ATM (0.80) | ATMALDH1A1POLBGLSHTT | |
| SCHEMBL14427584 | 0.71 | ALDH1A1 (0.76) | ATMALDH1A1POLBGLSLMNA | |
| SCHEMBL626076 | 0.71 | TAAR1 (0.68) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974043-A | Polq inhibitor compounds and uses thereof | 南京再明医药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023202623-A1 | POLQ INHIBITOR COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2023-10-26 | — | — | WO | disclosed |