SCHEMBL626076

SCHEMBL626076

Brc1ccc(CCc2ccc(Br)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.68
HTR2A P28223 1/20 0.68
CYP2A6 P11509 1/20 0.57
IDO1 P14902 3/20 0.50
GFER P55789 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
POLB P06746 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ALOX15 P16050 2/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1772877 0.88 TAAR1 (0.56) TAAR1HTR2ACYP2A6ALDH1A1ALOX15
SCHEMBL7904900 0.87 TAAR1 (0.62) TAAR1HTR2ACYP2A6IDO1MAPK1
SCHEMBL5238701 0.87 TAAR1 (0.62) TAAR1HTR2ACYP2A6IDO1MAPK1
SCHEMBL12011036 0.86 ALDH1A1 (0.68) TAAR1HTR2ACYP2A6IDO1ALDH1A1
SCHEMBL18550393 0.86 TAAR1 (0.54) TAAR1HTR2AIDO1POLB
SCHEMBL10355578 0.86 ESR1 (0.74) TAAR1HTR2AESR1ESR2ALDH1A1
SCHEMBL134452 0.84 TAAR1 (0.59) TAAR1HTR2ACYP2A6IDO1ESR1
SCHEMBL1520915 0.84 TAAR1 (0.59) TAAR1HTR2ACYP2A6IDO1POLB
SCHEMBL5645 0.84 TAAR1 (0.59) TAAR1HTR2ACYP2A6IDO1POLB
SCHEMBL15583726 0.84 TAAR1 (0.59) TAAR1HTR2ACYP2A6IDO1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930613-A Organic electroluminescent material based on pyrazine derivatives and preparation method and application thereof 海南师范大学 2025-05-06 CN claimed
CN-119613746-A Directably modified hexabenzo-metal organic framework, and preparation method and application thereof 南开大学 2025-03-14 CN claimed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN claimed
CN-117417248-B Molecular-level monolayer hydrophilic graphene quantum dot and preparation method thereof 武汉科技大学 2024-11-19 CN claimed
CN-118359500-A Single-layer water-soluble graphene quantum dot and preparation method and application thereof 武汉科技大学 2024-07-19 CN claimed
CN-117264211-A Low-melting-point polyarylene sulfide resin and film, and preparation methods and applications thereof 新凝合科技(成都)有限公司 2023-12-22 CN claimed
EP-0627463-A2 Flame retardant resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-12-07 EP claimed
JP-6345979-A None JP disclosed
EP-4438677-B1 RESIN COMPOSITION, RESINOUS COATING MATERIAL, INSULATED ELECTRICAL WIRE, AUTOMOTIVE WIRE HARNESS, AND METHOD FOR PRODUCING INSULATED ELECTRICAL WIRE FOR USE IN AUTOMOTIVE WIRE HARNESS FURUKAWA ELECTRIC CO LTD (JP) 2026-04-22 EP disclosed
US-12570785-B2 Thermoplastic polyurethane resin elastomers MITSUBISHI CHEMICAL CORPORATION (JP) 2026-03-10 US disclosed
US-12441874-B2 Resin composition, resin-coating material, insulated wire, vehicle wire harness, and method of producing insulated wire to be used in vehicle wire harness FURUKAWA ELECTRIC CO., LTD. (JP) 2025-10-14 US disclosed
CN-120117950-A Method for synthesizing 1, 2-di (4-vinyl phenyl) ethane 陕西巴斯腾科技有限公司 2025-06-10 CN disclosed
CN-120118025-A Preparation and multifunctional therapeutic application of D-A configuration single-molecule graphene quantum dot 武汉科技大学 2025-06-10 CN disclosed
US-6146554-A FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES OPTISCHE WERKE G. RODENSTOCK (DE) 2000-11-14 US disclosed
US-6068935-A EXCELLENT IN FLEXIBILITY, ABRASION RESISTANCE, HEAT RESISTANCE, AND THERMAL AGING RESISTANCE; UNSATURATED POLYESTER-LACTONE INTERPOLYMER SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2000-05-30 US disclosed
EP-0989147-A2 Thermoplastic polyester resin, and insulated wire, electrically insulated cable and heat-shrinkable tube each made with the resin Sumitomo Electric Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0848033-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1998-06-17 EP disclosed
JP-H06345979-A FLAME-RETARDANT RESIN COMPOSITION SUMITOMO ELECTRIC IND LTD 1994-12-20 JP disclosed
EP-0627463-A2 Flame retardant resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed
EP-0627463-A2 Flame retardant resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570785-B2 Thermoplastic polyurethane resin elastomers PUF60, INTS9, ADH1C TAAR1 2784/4885HTR2A 2918/4885CYP2A6 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.