Sugi Predict

Sugi Predict / Compounds / Trifluoroacetic Acid

Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL26599567

CN(C1CCNCC1)S(C)(=O)=O.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 15/20 0.36
▸ SLC6A4 P31645 15/20 0.36
▸ SLC6A3 Q01959 7/20 0.36
▸ GABRA1 P14867 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ GABRG2 P18507 2/20 0.33
▸ GABRB3 P28472 2/20 0.33
▸ GABRA5 P31644 2/20 0.33
▸ GABRA3 P34903 2/20 0.33
▸ GABRA2 P47869 2/20 0.33
▸ GABRA6 Q16445 2/20 0.33
▸ GABRP O00591 1/20 0.33
▸ GABRD O14764 1/20 0.33
▸ GABRB1 P18505 1/20 0.33
▸ GABRB2 P47870 1/20 0.33
▸ GABRA4 P48169 1/20 0.33
▸ GABRE P78334 1/20 0.33
▸ PMP22 Q01453 1/20 0.33
▸ GABRG1 Q8N1C3 1/20 0.33
▸ GABRG3 Q99928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296911 0.84 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL17240063 0.83 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL231312 0.82 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL5443966 0.81 GABRP (0.39) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL5443972 0.81 GABRP (0.39) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL7446778 0.81 GABRP (0.39) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL3006963 0.77 GABRP (0.35) SLC6A2SLC6A4SLC6A3GABRA1TSHR
Trifluoroacetic Acid SCHEMBL4194562 0.76 GABRA1 (0.45) SLC6A2SLC6A4GABRA1TSHRGABRG2
Trifluoroacetic Acid SCHEMBL8520995 0.75 SLC6A4 (0.42) SLC6A2SLC6A4SLC6A3CYP3A4KCNH2
Trifluoroacetic Acid SCHEMBL8435138 0.75 SLC6A4 (0.42) SLC6A2SLC6A4SLC6A3CYP3A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12454547-B2 Steroidal compositions and methods of treating lipogenic cancers Asteroid Therapeutics (US) 2025-10-28 — — US disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 — — US disclosed
WO-2023205801-A2 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics (US) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454547-B2 Steroidal compositions and methods of treating lipogenic cancers SREBF1, SREBF2, NR1H3 SLC6A2 4863/4885SLC6A4 4859/4885SLC6A3 4883/4885
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS SREBF1, SREBF2, NR1H3 SLC6A2 4863/4885SLC6A4 4859/4885SLC6A3 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.