SCHEMBL70795

SCHEMBL70795

Cc1nc(C)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.65
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
GABRP O00591 2/20 0.54
GABRD O14764 2/20 0.54
GABRA1 P14867 2/20 0.54
GABRB1 P18505 2/20 0.54
GABRG2 P18507 2/20 0.54
GABRB3 P28472 2/20 0.54
GABRA5 P31644 2/20 0.54
GABRA3 P34903 2/20 0.54
GABRA2 P47869 2/20 0.54
GABRB2 P47870 2/20 0.54
GABRA4 P48169 2/20 0.54
GABRE P78334 2/20 0.54
GABRA6 Q16445 2/20 0.54
GABRG1 Q8N1C3 2/20 0.54
GABRG3 Q99928 2/20 0.54
GABRQ Q9UN88 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9491457 0.97 SMN1; SMN2 (0.62) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL9315436 0.86 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL16616398 0.86 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL3507819 0.85 GAA (0.51) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL20472500 0.84 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL2804722 0.84 GABRP (0.55) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL30468364 0.84 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL30445660 0.84 GABRP (0.55) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL16616066 0.84 KEAP1 (0.55) SMN1; SMN2ALDH1A1MEN1KMT2AGABRP
SCHEMBL11470029 0.82 KDM4E (0.69) SMN1; SMN2ALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119587773-A Application of metal organic framework material in preparation of developing functional material, implantation intervention material, preparation method of implantation intervention material and implantation intervention instrument 中国科学院长春应用化学研究所 2025-03-11 CN claimed
CN-110041351-B Er (III) luminescent material containing phenanthroline, modified imidazole carboxylic acid and pyridine carboxylic acid mixed ligand and preparation method thereof 洛阳师范学院 2024-04-05 CN claimed
CN-117559076-A Cu-Ni-based MOF/MWCNT composite material modified diaphragm of lithium-sulfur battery and preparation method thereof 桂林理工大学 2024-02-13 CN claimed
CN-109824706-B Nd (III) compound luminescent material containing modified imidazole carboxylic acid and pyridine carboxylic acid mixed ligand and preparation method thereof 洛阳师范学院 2022-03-01 CN claimed
CN-109678897-B Nd compound luminescent material containing phenanthroline and modified carboxylic acid ligand and preparation method thereof 洛阳师范学院 2022-03-01 CN claimed
CN-113861797-A Preparation method and application of OPA (oriented architecture) super-hydrophobic modified material based on pyridine MOFs (metal-organic frameworks) 桂林理工大学 2021-12-31 CN claimed
CN-113831545-A Methyl side chain-containing pyridinedicarboxylic acid and 1, 10-phenanthroline-constructed europium coordination polymer and preparation method thereof 桂林理工大学 2021-12-24 CN claimed
CN-113717399-A Dysprosium coordination polymer constructed by picolinic acid containing methyl side chain and 1, 10-phenanthroline and preparation method thereof 桂林理工大学 2021-11-30 CN claimed
CN-113698622-A Methyl side chain-containing dipicolinic acid and 1, 10-phenanthroline-constructed terbium coordination polymer and preparation method thereof 桂林理工大学 2021-11-26 CN claimed
CN-103130822-B Preparation method of alkaline earth metal organic crystal material UNIV TAIYUAN TECHNOLOGY 2015-04-22 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
CN-103130822-A Preparation method of alkaline earth metal organic crystal material UNIV TAIYUAN TECHNOLOGY 2013-06-05 CN claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-119587773-A Application of metal organic framework material in preparation of developing functional material, implantation intervention material, preparation method of implantation intervention material and implantation intervention instrument 中国科学院长春应用化学研究所 2025-03-11 CN disclosed
CN-110041351-B Er (III) luminescent material containing phenanthroline, modified imidazole carboxylic acid and pyridine carboxylic acid mixed ligand and preparation method thereof 洛阳师范学院 2024-04-05 CN disclosed
CN-110041351-B Er (III) luminescent material containing phenanthroline, modified imidazole carboxylic acid and pyridine carboxylic acid mixed ligand and preparation method thereof 洛阳师范学院 2024-04-05 CN disclosed
WO-2000004018-A1 ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT CYBIO SCREENING GMBH (DE) 2000-01-27 WO disclosed
US-4556414-A Herbicidal dihydropyridine amides RHONE-POULENC AGROCHIMIE (FR) 1985-12-03 US disclosed
US-4201715-A Process for the anilidization of carboxylic acid esters WACKER-CHEMIE GMBH (DE) 1980-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SMN1; SMN2 4595/4885ALDH1A1 1901/4885MEN1 2029/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SMN1; SMN2 3730/4885ALDH1A1 1510/4885MEN1 748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.