Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30624653 | 1.00 | NPY5R (0.32) | NPY5RKDR | |
| SCHEMBL26602678 | 0.80 | KDM5B (0.33) | — | |
| SCHEMBL26676188 | 0.80 | CLK2 (0.33) | NPY5R | |
| SCHEMBL30695289 | 0.80 | CLK2 (0.33) | NPY5R | |
| SCHEMBL26601592 | 0.79 | EZH2 (0.36) | — | |
| SCHEMBL26707612 | 0.79 | ADORA2A (0.33) | — | |
| SCHEMBL26601605 | 0.78 | ADRA2A (0.32) | — | |
| SCHEMBL26601579 | 0.78 | IDO1 (0.33) | — | |
| SCHEMBL30624550 | 0.77 | KMO (0.35) | KDR | |
| SCHEMBL26601926 | 0.77 | KMO (0.35) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511117-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | Vertex Pharmaceuticals Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205465-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023205465-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-26 | — | — | WO | disclosed |