Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453060 | 1.00 | NPC1 (0.54) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453040 | 0.92 | GAA (0.48) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453054 | 0.91 | KMT2A (0.48) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453066 | 0.90 | ALDH1A1 (0.48) | NPC1RAB9AGAANR1H4MCL1 | |
| SCHEMBL31453046 | 0.90 | MCL1 (0.49) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453035 | 0.90 | NPC1 (0.57) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453037 | 0.89 | MCL1 (0.55) | NPC1RAB9AGAANR1H4MEN1 | |
| SCHEMBL31453051 | 0.88 | NPC1 (0.56) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL31453044 | 0.88 | HIF1A (0.50) | NPC1RAB9AGAANR1H4MCL1 | |
| SCHEMBL30671960 | 0.88 | HIF1A (0.57) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202578-A1 | GPCR REGULATOR AND USE THEREOF | 北京昌平实验室 | 2023-10-26 | — | — | WO | disclosed |