Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453060 | 0.90 | NPC1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2MCL1 | |
| SCHEMBL26602407 | 0.90 | NPC1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2MCL1 | |
| SCHEMBL31453044 | 0.87 | HIF1A (0.50) | ALDH1A1HPGDSMN1; SMN2MCL1KDM4E | |
| SCHEMBL31453046 | 0.87 | MCL1 (0.49) | ALDH1A1HPGDSMN1; SMN2MCL1KDM4E | |
| SCHEMBL31453054 | 0.84 | KMT2A (0.48) | ALDH1A1HPGDSMN1; SMN2LMNAMCL1 | |
| SCHEMBL31453037 | 0.82 | MCL1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL31453040 | 0.82 | GAA (0.48) | ALDH1A1HPGDSMN1; SMN2MCL1KDM4E | |
| SCHEMBL31453051 | 0.81 | NPC1 (0.56) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL31453035 | 0.80 | NPC1 (0.57) | ALDH1A1HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31453061 | 0.80 | MCL1 (0.46) | ALDH1A1HPGDSMN1; SMN2MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275958-A1 | GPCR REGULATOR AND USE THEREOF | Beijing Changping Laboratory (CN) | 2025-09-04 | — | — | US | disclosed |
| EP-4512803-A1 | GPCR REGULATOR AND USE THEREOF | Beijing Changping Laboratory (CN) | 2025-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275958-A1 | GPCR REGULATOR AND USE THEREOF | ARRB1, GPR3, GPR4 | ALDH1A1 2883/4885HPGD 1719/4885HTT 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.