Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | PAK4 | O96013 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23274765 | 0.93 | RAF1 (0.51) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL23275149 | 0.93 | RAF1 (0.51) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL26604092 | 0.93 | RAF1 (0.51) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL23274764 | 0.93 | RAF1 (0.51) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL30605621 | 0.90 | CCNT1 (0.47) | RAF1BRAFCCNT1FLT3GSK3B | |
| SCHEMBL26604157 | 0.89 | MAPK8 (0.43) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL26604154 | 0.89 | RAF1 (0.54) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL30605604 | 0.89 | RAF1 (0.54) | RAF1BRAFCCNT1CYP1A2CYP2D6 | |
| SCHEMBL26604142 | 0.87 | MAPK8 (0.52) | RAF1BRAFCCNT1FLT3TYRO3 | |
| SCHEMBL26604167 | 0.85 | HRH4 (0.57) | CCNT1FLT3TYRO3MERTKGAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |