Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605621 | 0.90 | CCNT1 (0.47) | HRH4FLT3MAPK8IRAK4MAPK9 | |
| SCHEMBL26604142 | 0.87 | MAPK8 (0.52) | HRH4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL30605618 | 0.87 | AURKA (0.43) | HRH4FLT3MAPK8IRAK4MAPK9 | |
| SCHEMBL26604157 | 0.86 | MAPK8 (0.43) | HRH4FLT3MAPK8IRAK4MAPK9 | |
| SCHEMBL26604064 | 0.86 | HRH4 (0.42) | HRH4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL30605629 | 0.86 | HRH4 (0.42) | HRH4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL26604103 | 0.85 | RAF1 (0.53) | HRH4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL30605624 | 0.84 | LMNA (0.44) | HRH4FLT3MAPK8IRAK4MAPK9 | |
| SCHEMBL26604171 | 0.84 | LMNA (0.44) | HRH4FLT3MAPK8IRAK4MAPK9 | |
| SCHEMBL30605610 | 0.82 | MAPK8 (0.41) | HRH4FLT3MAPK8IRAK4MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |