SCHEMBL26604142

SCHEMBL26604142

OC1CCC(Nc2nc(Cl)cc(N3CCCCC3)n2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 4/20 0.52
CHRM3 P20309 3/20 0.48
PDE4A P27815 3/20 0.48
PDE4B Q07343 3/20 0.48
PDE4C Q08493 3/20 0.48
PDE4D Q08499 3/20 0.48
NUDT1 P36639 1/20 0.48
HSD11B1 P28845 1/20 0.44
HRH4 Q9H3N8 2/20 0.44
FLT3 P36888 5/20 0.44
MAPK9 P45984 2/20 0.44
CDC7 O00311 1/20 0.44
CHEK1 O14757 1/20 0.44
AURKA O14965 1/20 0.44
MAPK13 O15264 1/20 0.44
PDPK1 O15530 1/20 0.44
DAPK3 O43293 1/20 0.44
DYRK3 O43781 1/20 0.44
JAK2 O60674 1/20 0.44
PRKD3 O94806 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30605621 0.92 CCNT1 (0.47) MAPK8CHRM3PDE4APDE4BPDE4C
SCHEMBL26604157 0.88 MAPK8 (0.43) MAPK8CHRM3PDE4APDE4BPDE4C
SCHEMBL9085486 0.88 HRH4 (0.56) MAPK8CHRM3PDE4APDE4BPDE4C
SCHEMBL26604103 0.87 RAF1 (0.53) MAPK8HRH4FLT3MAPK9CDC7
SCHEMBL26604167 0.87 HRH4 (0.57) MAPK8HRH4FLT3MAPK9CDC7
SCHEMBL30605624 0.84 LMNA (0.44) MAPK8HRH4FLT3MAPK9CDC7
SCHEMBL30605618 0.84 AURKA (0.43) MAPK8HRH4FLT3MAPK9CDC7
SCHEMBL26604171 0.84 LMNA (0.44) MAPK8HRH4FLT3MAPK9CDC7
SCHEMBL30605610 0.84 MAPK8 (0.41) MAPK8CHRM3PDE4APDE4BPDE4C
SCHEMBL30605629 0.83 HRH4 (0.42) MAPK8HRH4FLT3MAPK9CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023204642-A1 PROTEIN KINASE INHIBITOR AND USE THEREOF (주)메디톡스 2023-10-26 WO disclosed