Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24847031 | 0.87 | MAPT (0.56) | MAPTALDH1A1LMNAGPR119PDK2 | |
| SCHEMBL21667796 | 0.85 | MAPT (0.54) | MAPTALDH1A1LMNAGPR119CKS1B | |
| SCHEMBL12781530 | 0.85 | MAPT (0.52) | MAPTALDH1A1LMNASUV39H2GPR119 | |
| SCHEMBL16892111 | 0.84 | GPR119 (0.56) | MAPTALDH1A1LMNAGPR119CKS1B | |
| SCHEMBL29632731 | 0.84 | MEN1 (0.54) | LMNAKCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL805892 | 0.84 | MAPT (0.53) | MAPTALDH1A1LMNASUV39H2GPR119 | |
| SCHEMBL7581350 | 0.84 | MAPT (0.53) | MAPTALDH1A1LMNAKCNH2SUV39H2 | |
| SCHEMBL31623073 | 0.83 | MAPT (0.52) | MAPTALDH1A1LMNAKCNH2GPR119 | |
| SCHEMBL22309127 | 0.82 | CKS1B (0.49) | MAPTALDH1A1LMNAKCNH2SUV39H2 | |
| SCHEMBL5683429 | 0.82 | MAPT (0.57) | MAPTALDH1A1LMNAGPR119PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |