Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.47 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085087 | 0.90 | MAPT (0.63) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL23321223 | 0.87 | LMNA (0.64) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL26604082 | 0.86 | KMT2A (0.68) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL21313535 | 0.86 | MAPT (0.52) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL13632492 | 0.86 | MAPT (0.49) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL28057244 | 0.85 | MAPT (0.51) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL1028449 | 0.80 | CHEK1 (0.53) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL9645141 | 0.77 | AURKA (0.53) | MAPTPTGS2MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL14804579 | 0.76 | CYP1A2 (0.60) | RAF1BRAFMAPTCYP1A2CYP2D6 | |
| SCHEMBL21313483 | 0.76 | MAPT (0.50) | RAF1BRAFMAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |