Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | YES1 | P07947 | 2/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959433 | 0.83 | AURKA (0.59) | AURKAKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL13632493 | 0.82 | GAA (0.54) | AURKAKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL1391141 | 0.82 | NFKB1 (0.64) | AURKAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL17943198 | 0.80 | NPC1 (0.56) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL9646257 | 0.80 | AURKA (0.53) | AURKAKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL658190 | 0.79 | SYK (0.59) | KMT2AMEN1SYKPOLBNFKB1 | |
| SCHEMBL9647947 | 0.79 | AURKA (0.72) | AURKAKMT2AMEN1MAPTSYK | |
| SCHEMBL3241000 | 0.79 | MAPT (0.67) | AURKAKMT2AMEN1GAAMAPT | |
| SCHEMBL26604115 | 0.77 | RAF1 (0.54) | AURKAKMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL8136796 | 0.77 | TXN (0.54) | AURKAKMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372623-A2 | Flame-resistant polycarbonates containing units deriving from halogenated pyrimidine compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-13 | — | — | EP | claimed |
| US-5166306-A | Self-extinguishing polycarbonates | ENICHEM TECHNORESINE S.P.A. (IT) | 1992-11-24 | — | — | US | disclosed |
| US-5098989-A | Copolymers that are self-extinguishing formed by reaction of carbonate precursor, a dihydroxyaromatic compound and a halogenated pyrimidine and a branching compound | ENICHEM TECNORESINE S.P.A. (IT) | 1992-03-24 | — | — | US | disclosed |
| EP-0372623-A2 | Flame-resistant polycarbonates containing units deriving from halogenated pyrimidine compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |