Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21193554 | 0.86 | GBA1 (0.66) | GBA1SMOCKS1BSKP1SKP2 | |
| SCHEMBL18153268 | 0.86 | HRH4 (0.41) | GBA1HRH4LMNAMAPTKMT2A | |
| SCHEMBL19691058 | 0.84 | GBA1 (0.52) | GBA1SMOCKS1BSKP1SKP2 | |
| SCHEMBL16505690 | 0.82 | LMNA (0.51) | GBA1SMOCKS1BSKP1SKP2 | |
| SCHEMBL12069783 | 0.82 | GBA1 (0.48) | GBA1SMOCKS1BSKP1SKP2 | |
| SCHEMBL19687408 | 0.80 | GBA1 (0.46) | GBA1SMOCKS1BSKP1SKP2 | |
| SCHEMBL3991539 | 0.80 | CKS1B (0.50) | CKS1BSKP1SKP2HRH4MAP4K4 | |
| SCHEMBL19690964 | 0.79 | CASP6 (0.51) | GBA1NCF1CLK1TP53MAPT | |
| SCHEMBL2336863 | 0.78 | HRH4 (0.66) | HRH4 | |
| SCHEMBL14276922 | 0.78 | SMO (0.50) | GBA1SMOCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204642-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2023-10-26 | — | — | WO | disclosed |