Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659558 | 0.93 | ALDH1A1 (0.35) | SMN1; SMN2HSD17B10PKMLMNA | |
| Trifluoroacetic Acid SCHEMBL2978056 | 0.92 | HSD17B10 (0.40) | SMN1; SMN2HSD17B10PKMLMNATSHR | |
| SCHEMBL2668547 | 0.91 | HSD17B10 (0.44) | SMN1; SMN2HSD17B10PKMLMNATSHR | |
| SCHEMBL2659475 | 0.89 | ALDH1A1 (0.37) | SMN1; SMN2HSD17B10PKMLMNATSHR | |
| SCHEMBL2967154 | 0.89 | OPRM1 (0.32) | LMNATSHR | |
| Trifluoroacetic Acid SCHEMBL2661305 | 0.88 | SLC2A1 (0.32) | LMNA | |
| SCHEMBL2977364 | 0.88 | — | — | |
| Trifluoroacetic Acid SCHEMBL2661336 | 0.88 | KDM4E (0.31) | SMN1; SMN2PKMLMNATSHR | |
| Trifluoroacetic Acid SCHEMBL2660463 | 0.88 | HDAC1 (0.32) | SMN1; SMN2LMNA | |
| SCHEMBL2968235 | 0.87 | GCK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |