Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611992 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKMT2AMEN1RXFP1 | |
| SCHEMBL26611719 | 0.86 | MTNR1A (0.39) | ALDH1A1KMT2AMEN1RXFP1RAB9A | |
| SCHEMBL26611757 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL31414675 | 0.84 | BRD4 (0.43) | ALDH1A1MAPTHTTPOLB | |
| SCHEMBL26698054 | 0.84 | BRD4 (0.43) | ALDH1A1MAPTHTTPOLB | |
| SCHEMBL26611516 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL26611517 | 0.83 | KMT2A (0.36) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL26611482 | 0.82 | MTNR1A (0.43) | ALDH1A1KMT2AMEN1CA12CA1 | |
| SCHEMBL26611576 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL26612275 | 0.81 | NSD2 (0.42) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |