Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414661 | 0.85 | DRD2 (0.39) | MTNR1AMTNR1BNQO2EPHX1 | |
| SCHEMBL26699241 | 0.85 | DRD2 (0.39) | MTNR1AMTNR1BNQO2EPHX1 | |
| SCHEMBL26611752 | 0.82 | SMN1; SMN2 (0.39) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL26611992 | 0.81 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL26611757 | 0.80 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL26611719 | 0.80 | MTNR1A (0.39) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL26612108 | 0.80 | ACACB (0.36) | MTNR1AMTNR1BNQO2LRRK2 | |
| SCHEMBL31414697 | 0.78 | HTR2A (0.50) | — | |
| SCHEMBL26612257 | 0.78 | HTR2A (0.50) | — | |
| SCHEMBL26611516 | 0.78 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |