Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.76 |
| ▸ | ALK | Q9UM73 | 14/20 | 0.67 |
| ▸ | INSR | P06213 | 4/20 | 0.65 |
| ▸ | IGF1R | P08069 | 4/20 | 0.65 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611923 | 0.97 | EGFR (0.76) | EGFRALKINSRIGF1RMAPK3 | |
| SCHEMBL26611456 | 0.92 | EGFR (0.74) | EGFRALKINSRIGF1RMAPK3 | |
| SCHEMBL26612255 | 0.91 | EGFR (0.77) | EGFRALKINSRIGF1R | |
| SCHEMBL26611568 | 0.90 | EGFR (0.74) | EGFRALKINSRIGF1R | |
| SCHEMBL26611925 | 0.90 | EGFR (0.75) | EGFRALKINSRIGF1R | |
| SCHEMBL26611721 | 0.89 | EGFR (0.77) | EGFRALKINSRIGF1R | |
| SCHEMBL26612055 | 0.88 | EGFR (0.75) | EGFRALKINSRIGF1R | |
| SCHEMBL26612137 | 0.88 | ALK (0.72) | EGFRALKINSRIGF1R | |
| SCHEMBL26611707 | 0.87 | EGFR (0.75) | EGFRALKINSRIGF1R | |
| SCHEMBL26611961 | 0.86 | EGFR (0.72) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |