Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498010 | 0.81 | BCAT2 (0.54) | DHODHCHEK1XDHDYRK1ABCAT2 | |
| SCHEMBL16193974 | 0.80 | IGF2BP2 (0.44) | CHEK1ABL1BCAT2PDK2SCN9A | |
| SCHEMBL2114962 | 0.79 | BCAT2 (0.52) | ABL1BCAT2PDK2 | |
| SCHEMBL5379608 | 0.76 | ESR1 (0.55) | DHODHPIM1PIM2ABL1XDH | |
| SCHEMBL16193827 | 0.76 | ESR2 (0.42) | ABL1BCAT2PDK2 | |
| SCHEMBL16194153 | 0.74 | FFAR4 (0.39) | CHEK1ABL1PDK2SCN9A | |
| SCHEMBL2562027 | 0.74 | BCAT2 (0.59) | CHEK1ABL1SERPINE1BCAT2SCN9A | |
| SCHEMBL14813212 | 0.72 | CHEK1 (0.49) | CHEK1ABL1SERPINE1BCAT2SCN9A | |
| SCHEMBL6174664 | 0.72 | KCNA5 (0.49) | DHODHDYRK1ACSNK1E | |
| SCHEMBL4517767 | 0.71 | BCAT2 (0.51) | CHEK1PIM1ABL1BCAT2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782616-B1 | ESTROGEN RECEPTOR LIGAND TREATMENT FOR NEURODEGENERATIVE DISEASES | UNIV CALIFORNIA (US) | 2023-11-01 | — | — | EP | disclosed |