SCHEMBL26612937

SCHEMBL26612937

C1=c2ccccc2=CC=c2ccccc2=C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 0.39
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TSHR P16473 5/20 0.33
LMNA P02545 3/20 0.33
CA2 P00918 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
CYP3A4 P08684 2/20 0.33
ALOX15 P16050 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CA12 O43570 2/20 0.33
CA3 P07451 2/20 0.33
MAPT P10636 2/20 0.33
CA4 P22748 2/20 0.33
CA14 Q9ULX7 2/20 0.33
ACHE P22303 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5888763 1.00
SCHEMBL1233170 0.82
SCHEMBL25092 0.64
SCHEMBL3991516 0.61 CYP2A6 (0.31) ALOX12CYP2A6TSHR
Naphthalene SCHEMBL250705 0.60 CYP2A6 (0.80) ALOX12CYP2A6ALDH1A1TSHRCA2
Ethylene SCHEMBL8984232 0.60 MEN1 (0.53) ALOX12CYP2A6ALDH1A1TSHRLMNA
Naphthalene SCHEMBL3614510 0.60 CYP2A6 (0.80) ALOX12CYP2A6ALDH1A1TSHRCA2
Ethylene SCHEMBL8984236 0.60 ALOX12 (0.39) ALOX12CYP2A6ALDH1A1TSHRLMNA
Ethylene SCHEMBL5397976 0.60 MEN1 (0.53) ALOX12CYP2A6ALDH1A1TSHRLMNA
Biphenyl SCHEMBL5586130 0.57 ALDH1A1 (0.82) CYP2A6ALDH1A1LMNACA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115460-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-06-06 WO disclosed
WO-2024068860-A1 OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-04-04 WO disclosed
WO-2023208837-A1 OLIGOMERIC BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-11-02 WO disclosed
WO-2023210833-A1 OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-02 WO disclosed