Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619312 | 0.85 | KDM4E (0.50) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1647161 | 0.84 | NR4A2 (0.52) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1646920 | 0.84 | KDM4E (0.49) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1646960 | 0.83 | KDM4E (0.48) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL9904829 | 0.82 | GPR84 (0.59) | KDM4ENR4A2GPR84ASH1LALDH1A1 | |
| SCHEMBL1647163 | 0.81 | KDM4E (0.52) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1647166 | 0.81 | KDM4E (0.52) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL31464238 | 0.77 | KDM4E (0.55) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1646994 | 0.77 | KDM4E (0.55) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL27997808 | 0.76 | KDM4E (0.69) | KDM4EKDM6BKDM5CKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289809-A1 | COMPOUNDS USEFUL FOR GOUT | ATOM BIOSCIENCE AMERICA CORPORATION (US) | 2025-09-18 | — | — | US | disclosed |
| EP-4516788-A1 | COMPOUND CAPABLE OF BEING USED FOR GOUT | Atom Therapeutics Co., Ltd (CN) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023208103-A1 | COMPOUND CAPABLE OF BEING USED FOR GOUT | 江苏新元素医药科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116836154-A | Compounds useful for gout | 江苏新元素医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289809-A1 | COMPOUNDS USEFUL FOR GOUT | SLC10A1, ABCG2, SLC10A6 | KDM4E 3183/4885KDM6B 2997/4885KDM5C 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.