Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616548 | 1.00 | ACE (0.60) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL26616386 | 0.97 | ACE (0.64) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL31376307 | 0.97 | ACE (0.64) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL26616380 | 0.97 | ACE (0.64) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL26616455 | 0.97 | ACE (0.64) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL26616457 | 0.97 | ACE (0.64) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL26616418 | 0.92 | ACE (0.53) | ACELMNALTA4HSMN1; SMN2MEN1 | |
| SCHEMBL26616411 | 0.92 | ACE (0.53) | ACELMNALTA4HSMN1; SMN2MEN1 | |
| SCHEMBL30674429 | 0.91 | ACE (0.50) | ACELMNAMEN1NPC1RAB9A | |
| SCHEMBL9814474 | 0.90 | ACE (0.67) | ACELMNALTA4HSMN1; SMN2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514781-A1 | PREP BINDING LIGANDS | Polku Therapeutics OY (FI) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |