Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091242 | 0.75 | LMNA (0.47) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL29892233 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL5843250 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL1886976 | 0.73 | POLB (0.45) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL30124712 | 0.73 | POLB (0.45) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL26608375 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL20260106 | 0.71 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL13237026 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL12597876 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA | |
| SCHEMBL26608285 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |