Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19224646 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPSR1CES1L3MBTL1MAPT | |
| SCHEMBL18039456 | 0.70 | NPSR1 (0.47) | ALDH1A1NPSR1L3MBTL1MAPTTSHR | |
| SCHEMBL6900380 | 0.70 | ALDH1A1 (0.40) | ALDH1A1NPSR1CES1L3MBTL1MAPT | |
| SCHEMBL7367074 | 0.69 | CES1 (0.41) | ALDH1A1NPSR1CES1MAPTTSHR | |
| SCHEMBL19948875 | 0.67 | ALDH1A1 (0.40) | ALDH1A1NPSR1CES1L3MBTL1MAPT | |
| SCHEMBL164310 | 0.66 | RAF1 (0.38) | ALDH1A1NPSR1L3MBTL1MAPTTSHR | |
| SCHEMBL12894510 | 0.66 | ALDH1A1 (0.45) | ALDH1A1NPSR1L3MBTL1MAPTTSHR | |
| SCHEMBL19948901 | 0.66 | ALDH1A1 (0.38) | ALDH1A1NPSR1CES1MAPTKMT2A | |
| SCHEMBL20263330 | 0.66 | ALDH1A1 (0.38) | ALDH1A1NPSR1MAPTTSHRKMT2A | |
| SCHEMBL2251389 | 0.65 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353860-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | BRISE PHARMACEUTICALS CO., LTD. (CN) | 2025-11-20 | — | — | US | disclosed |
| EP-4516793-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | Brise Pharmaceuticals Co., Ltd. (CN) | 2025-03-05 | — | — | EP | disclosed |
| CN-117003762-A | Piperidine formamide aza indane derivative, preparation method and application thereof | 熙源安健医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023208124-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 熙源安健医药（上海）有限公司 | 2023-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353860-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | CALCR, CNR2, CALCRL | ALDH1A1 1732/4885NPSR1 112/4885CES1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.