Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GCG | P01275 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662252 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBMAPTLMNA | |
| SCHEMBL2662005 | 0.83 | GAA (0.54) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL3199273 | 0.74 | POLB (0.80) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL4091220 | 0.72 | GCGR (0.44) | MAPTGCGMEN1KMT2A | |
| SCHEMBL2663140 | 0.71 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL2665712 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1GCGCA1 | |
| SCHEMBL2662250 | 0.70 | NAMPT (0.48) | ALDH1A1SMN1; SMN2GAAPOLBMAPT | |
| SCHEMBL3187109 | 0.69 | KDM4E (0.64) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL4886486 | 0.68 | KMT2A (0.60) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL4886493 | 0.68 | KMT2A (0.60) | ALDH1A1SMN1; SMN2POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183229-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |