Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.47 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.47 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.47 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.47 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601086 | 0.84 | NAAA (0.63) | SMN1; SMN2HDAC1TAOK1TAOK3NPC1 | |
| SCHEMBL5039785 | 0.84 | NAAA (0.63) | SMN1; SMN2HDAC1TAOK1TAOK3NPC1 | |
| SCHEMBL5048823 | 0.84 | NAAA (0.63) | SMN1; SMN2HDAC1TAOK1TAOK3NPC1 | |
| SCHEMBL21153228 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2HDAC1NPC1RAB9AHDAC6 | |
| SCHEMBL25360452 | 0.77 | CYP3A4 (0.59) | SMN1; SMN2 | |
| SCHEMBL2749557 | 0.77 | CYP3A4 (0.59) | SMN1; SMN2 | |
| SCHEMBL27943340 | 0.77 | CYP3A4 (0.59) | SMN1; SMN2 | |
| SCHEMBL14469578 | 0.77 | SMN1; SMN2 (0.82) | SMN1; SMN2 | |
| SCHEMBL9072937 | 0.75 | CA1 (0.52) | HDAC1HDAC6GCGREPHX2CA1 | |
| Betamipron SCHEMBL605899 | 0.75 | PRSS1 (0.70) | SMN1; SMN2HDAC1NPC1RAB9AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |