Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640500 | 1.00 | LPL (0.36) | LPLLIPGMAPTKDM4EALDH1A1 | |
| SCHEMBL30319501 | 0.84 | LPL (0.31) | LPLLIPG | |
| SCHEMBL16048555 | 0.83 | LPL (0.36) | LPLLIPGMAPTKDM4E | |
| SCHEMBL12148735 | 0.79 | LPL (0.38) | LPLLIPG | |
| SCHEMBL14727554 | 0.75 | LPL (0.43) | LPLLIPGMAPTKDM4EALDH1A1 | |
| SCHEMBL20571666 | 0.75 | TRPM5 (0.30) | — | |
| SCHEMBL30640493 | 0.74 | LPL (0.36) | LPLLIPG | |
| SCHEMBL26621958 | 0.74 | LPL (0.36) | LPLLIPG | |
| SCHEMBL16048411 | 0.73 | LPL (0.36) | LPLLIPGMAPTKDM4E | |
| SCHEMBL29307411 | 0.73 | LPL (0.35) | LPLLIPGMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |