Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.62 |
| ▸ | CASP3 | P42574 | 9/20 | 0.61 |
| ▸ | CASP8 | Q14790 | 8/20 | 0.61 |
| ▸ | CASP6 | P55212 | 6/20 | 0.61 |
| ▸ | CASP9 | P55211 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26623257 | 1.00 | CASP1 (0.62) | CASP1CASP3CASP8CASP6CASP9 | |
| SCHEMBL20827575 | 0.88 | CASP3 (0.56) | CASP1CASP3CASP8CASP6CASP9 | |
| SCHEMBL78880 | 0.87 | CASP3 (0.51) | CASP1CASP3CASP8CASP6 | |
| SCHEMBL20980797 | 0.87 | CASP3 (0.53) | CASP1CASP3CASP8CASP6 | |
| SCHEMBL78881 | 0.87 | CASP3 (0.51) | CASP1CASP3CASP8CASP6 | |
| SCHEMBL20827576 | 0.85 | CASP3 (0.62) | CASP3 | |
| SCHEMBL22862226 | 0.83 | KLK7 (0.54) | CASP1CASP3CASP8CASP6CASP9 | |
| SCHEMBL7199250 | 0.82 | CASP3 (0.77) | CASP3CASP8CASP6 | |
| SCHEMBL20827256 | 0.81 | CASP3 (0.78) | CASP3 | |
| SCHEMBL17261859 | 0.81 | CASP3 (0.59) | CASP3CASP8CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |