Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 1/20 | 0.50 |
| ▸ | POLQ | O75417 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257708 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAOBLMNAMAOAIAPP | |
| SCHEMBL6286074 | 0.90 | MAOB (0.46) | ALDH1A1MAOBLMNAMAOAIAPP | |
| SCHEMBL27872108 | 0.85 | IDO1 (0.47) | ALDH1A1MAOBMAOAPOLQHDAC1 | |
| SCHEMBL7400128 | 0.85 | HDAC1 (0.50) | ALDH1A1MAOBLMNAMAOAPOLQ | |
| SCHEMBL15932777 | 0.85 | IAPP (0.50) | ALDH1A1MAOBLMNAMAOAIAPP | |
| SCHEMBL29733422 | 0.84 | EPHX2 (0.59) | ALDH1A1POLQHDAC1HDAC8CNR1 | |
| SCHEMBL1953231 | 0.84 | EPHX2 (0.59) | ALDH1A1POLQHDAC1HDAC8CNR1 | |
| SCHEMBL23662783 | 0.83 | IAPP (0.53) | ALDH1A1MAOBMAOAIAPPPOLQ | |
| SCHEMBL21576141 | 0.83 | POLQ (0.47) | ALDH1A1MAOBMAOAPOLQHDAC1 | |
| SCHEMBL3233422 | 0.82 | MAOB (0.50) | ALDH1A1MAOBMAOAPOLQHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| CN-115836062-A | Compound and medical application thereof | 心悦生医股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
| WO-2021046549-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| US-8431378-B2 | Aminotransferase, gene encoding the same, and methods of using them | KANEKA CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20120164724-A1 | NOVEL AMINOTRANSFERASE, GENE ENCODING THE SAME, AND METHODS OF USING THEM | KANEKA CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| US-8133705-B2 | Aminotransferase, gene encoding the same, and method of using them | KANEKA CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20100285544-A1 | Novel aminotransferase, gene encoding the same, and method of using them | KANEKA CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-1889907-B1 | NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME | KANEKA CORP (JP) | 2009-09-02 | — | — | EP | disclosed |
| EP-1889907-A1 | NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-20060264653-A1 | Aminoacetonitrile derivatives and their use for controlling parasites | DUCRAY PIERRE | 2006-11-23 | — | — | US | disclosed |
| US-7091371-B2 | Aminoacetonitrile derivatives and their use for controlling parasites | NOVARTIS ANIMAL HEALTH US, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050033081-A1 | Aminoacetonitrile derivatives and their use for controlling parasites | NOVARTIS AG (CH) | 2005-02-10 | — | — | US | disclosed |
| EP-1456170-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES | Novartis AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003048112-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES | NOVARTIS AG (CH) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | HRH4, OR10J3, CYP3A5 | ALDH1A1 654/4885MAOB 1547/4885LMNA 4372/4885 |
| US-20050033081-A1 | Aminoacetonitrile derivatives and their use for controlling parasites | NAT1, ALDH7A1, AAAS | ALDH1A1 48/4885MAOB 1036/4885LMNA 2409/4885 |
| US-20060264653-A1 | Aminoacetonitrile derivatives and their use for controlling parasites | AAAS, NAT1, ALDH7A1 | ALDH1A1 74/4885MAOB 1027/4885LMNA 2402/4885 |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | HRH4, OR10J3, CYP3A5 | ALDH1A1 654/4885MAOB 1547/4885LMNA 4372/4885 |
| US-20100285544-A1 | Novel aminotransferase, gene encoding the same, and method of using them | BCAT1, AGXT, ALDH7A1 | ALDH1A1 144/4885MAOB 1260/4885LMNA 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.