Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653362 | 0.86 | ALDH1A1 (0.35) | MAPT | |
| SCHEMBL2968702 | 0.85 | MAPT (0.35) | MAPT | |
| SCHEMBL28780320 | 0.85 | EDNRB (0.35) | — | |
| SCHEMBL27762835 | 0.84 | EDNRB (0.34) | — | |
| SCHEMBL13348338 | 0.81 | MAPT (0.34) | MAPT | |
| SCHEMBL1654482 | 0.79 | ALDH1A1 (0.34) | MAPT | |
| SCHEMBL1653719 | 0.77 | ALDH1A1 (0.38) | MAPT | |
| SCHEMBL2660296 | 0.76 | ALDH1A1 (0.36) | MAPT | |
| SCHEMBL1653460 | 0.74 | TSHR (0.34) | MAPT | |
| SCHEMBL1653982 | 0.74 | ALDH1A1 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |