Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968702 | 0.94 | MAPT (0.35) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL1653362 | 0.93 | ALDH1A1 (0.35) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL13348488 | 0.90 | ALDH1A1 (0.36) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL1654129 | 0.88 | MAPT (0.33) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL1653982 | 0.86 | ALDH1A1 (0.34) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL1654482 | 0.85 | ALDH1A1 (0.34) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL2659949 | 0.85 | ALDH1A1 (0.37) | MAPTALDH1A1OXTRKMT2AHPGD | |
| SCHEMBL2660296 | 0.83 | ALDH1A1 (0.36) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL1653719 | 0.82 | ALDH1A1 (0.38) | MAPTALDH1A1OXTRTSHRKMT2A | |
| SCHEMBL2662680 | 0.81 | MAPT (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144702-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20090286975-A1 | Indole compound | YASUMA TSUNEO | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144702-A1 | INDOLE COMPOUND | GCKR, GPR119, SLC5A1 | MAPT 4224/4885ALDH1A1 376/4885OXTR 1731/4885 |
| US-20090286975-A1 | Indole compound | GCKR, GPR119, SLC5A1 | MAPT 4224/4885ALDH1A1 376/4885OXTR 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.