Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294154 | 0.87 | NOS1 (0.42) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL2962664 | 0.83 | NOS1 (0.37) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL856794 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL20496961 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL67349 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HLMNA | |
| SCHEMBL25412373 | 0.82 | NOS1 (0.43) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL17449764 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HLMNA | |
| SCHEMBL5763676 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HLMNA | |
| SCHEMBL2611904 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HCYP3A4 | |
| SCHEMBL67350 | 0.82 | NOS1 (0.40) | NOS1NOS3NOS2LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202625-A1 | FGFR2 INHIBITOR AND METHOD FOR USING SAME | 深圳福沃药业有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-1091741-A | Tartronic acid and acetal ether thereof and O-ester | DOMPE FARMACEUTICI SPA (IT) | 1994-09-07 | — | — | CN | disclosed |