Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216860 | 0.79 | HTR2B (0.69) | HTR2BACHECYP2C19IRAK4HTR2C | |
| Ammonia Solution, Strong SCHEMBL27976670 | 0.78 | HTR2B (0.68) | HTR2BACHECYP2C19IRAK4HTR2C | |
| SCHEMBL31351218 | 0.75 | HTR2B (0.60) | HTR2BACHECYP2C19TLR7 | |
| SCHEMBL17515109 | 0.75 | CYP2A6 (0.46) | TGFBR1 | |
| SCHEMBL2100275 | 0.75 | HTR2B (0.59) | HTR2BACHECYP2C19TLR7ALDH1A1 | |
| SCHEMBL22583027 | 0.74 | CYP2A6 (0.41) | PIM1TGFBR1 | |
| SCHEMBL29435604 | 0.74 | CYP2A6 (0.41) | PIM1TGFBR1 | |
| SCHEMBL21553220 | 0.74 | PIM1 (0.51) | PIM1TLR7IRAK4 | |
| SCHEMBL13726372 | 0.74 | ADORA3 (0.41) | TGFBR1 | |
| SCHEMBL28309488 | 0.74 | TGFBR1 (0.48) | TGFBR1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024082724-A1 | PIM KINASE INHIBITOR IN COMBINATION WITH KRAS INHIBITOR | NINGBO NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-04-25 | — | — | WO | disclosed |
| WO-2023202563-A1 | AKT INHIBITOR IN COMBINATION WITH PIM KINASE INHIBITOR | NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-10-26 | — | — | WO | disclosed |