Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 11/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626622 | 0.79 | PIM1 (0.59) | KMT2ARAB9ANPC1KDM4EHTT | |
| Ammonia Solution, Strong SCHEMBL27976383 | 0.78 | PIM1 (0.57) | KMT2ARAB9ANPC1KDM4EHTT | |
| SCHEMBL7368441 | 0.75 | L3MBTL1 (0.69) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL2100277 | 0.75 | NPC1 (0.58) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL28703760 | 0.74 | RAB9A (0.81) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL29376441 | 0.74 | RAB9A (0.81) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL1558713 | 0.74 | RAB9A (0.70) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL7532358 | 0.74 | KMT2A (0.68) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL30421156 | 0.73 | RAB9A (0.65) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL5629538 | 0.73 | RAB9A (0.65) | L3MBTL1KMT2ARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024082724-A1 | PIM KINASE INHIBITOR IN COMBINATION WITH KRAS INHIBITOR | NINGBO NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-04-25 | — | — | WO | disclosed |
| WO-2023202563-A1 | AKT INHIBITOR IN COMBINATION WITH PIM KINASE INHIBITOR | NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-10-26 | — | — | WO | disclosed |