Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.55 |
| ▸ | GCGR | P47871 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689130 | 0.93 | ALDH1A1 (0.57) | GCGRLMNATP53KDM4EALDH1A1 | |
| SCHEMBL2646215 | 0.88 | GCGR (0.52) | MAPK14GCGRALOX5 | |
| SCHEMBL2644649 | 0.83 | MAPK14 (0.58) | MAPK14GCGRALOX5 | |
| SCHEMBL4173953 | 0.82 | MDM2 (0.49) | LMNATP53KDM4EALDH1A1GAA | |
| SCHEMBL4184780 | 0.82 | CSNK1A1 (0.62) | MAPK14GCGRLMNATP53KDM4E | |
| SCHEMBL7696380 | 0.82 | CSNK1A1 (0.62) | MAPK14GCGRLMNATP53KDM4E | |
| SCHEMBL7686682 | 0.80 | AR (0.64) | GCGRTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL22589255 | 0.78 | MAPK14 (0.52) | MAPK14GCGRALOX5 | |
| SCHEMBL5647424 | 0.78 | MAPK14 (0.55) | MAPK14GCGRALOX5CDC7 | |
| SCHEMBL31567905 | 0.78 | ALDH1A1 (0.62) | LMNATP53KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016441-A1 | SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |