Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804954 | 0.87 | GCGR (0.49) | TP53ALDH1A1MAPTHPGDGAA | |
| SCHEMBL4163228 | 0.84 | PTGS2 (0.40) | ALDH1A1MAPTKDM4ERAB9AMEN1 | |
| SCHEMBL2648462 | 0.82 | GRM6 (0.44) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL2662802 | 0.82 | MAPK14 (0.55) | MDM2TP53ALDH1A1MAPTHPGD | |
| SCHEMBL2662901 | 0.81 | GRM6 (0.46) | MDM2TP53ALDH1A1MAPTHPGD | |
| SCHEMBL5821884 | 0.81 | RAB9A (0.45) | MDM2TP53ALDH1A1MAPTHPGD | |
| SCHEMBL1126493 | 0.81 | MAPT (0.53) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL17309573 | 0.81 | MAPK14 (0.41) | ALDH1A1MAPTKDM4EGAARAB9A | |
| SCHEMBL9152019 | 0.79 | GCGR (0.46) | TP53ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL9664732 | 0.79 | GCGR (0.48) | MDM2TP53ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084827-A2 | SYNTHETIC INTERMEDIATES, PROCESS FOR PREPARING PYRROLYLHEPTANOIC ACID DERIVATIVES THEREFROM | DONG-A PHARM.CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |
| WO-2007107276-A2 | PROCESS FOR PREPARING C7 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |
| EP-1834944-A1 | Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives | Ratiopharm GmbH (DE) | 2007-09-19 | — | — | EP | disclosed |