Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26629359 | 0.83 | ADRA1D (0.38) | ADRA1D | |
| SCHEMBL26629189 | 0.81 | ADRA1D (0.41) | ADRA1D | |
| SCHEMBL30635678 | 0.77 | ADRA1D (0.34) | ADRA1D | |
| SCHEMBL26779629 | 0.75 | ADRA1D (0.33) | ADRA1D | |
| SCHEMBL26629385 | 0.74 | ADRA1D (0.36) | ADRA1D | |
| SCHEMBL13919765 | 0.69 | — | — | |
| SCHEMBL26629171 | 0.69 | ADRA1D (0.33) | ADRA1D | |
| SCHEMBL2478962 | 0.68 | ADRA1D (0.38) | ADRA1D | |
| SCHEMBL28811183 | 0.68 | — | — | |
| SCHEMBL18003233 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |