Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26629359 | 0.78 | ADRA1D (0.38) | ADRA1D | |
| SCHEMBL26629385 | 0.76 | ADRA1D (0.36) | ADRA1D | |
| SCHEMBL26629137 | 0.75 | ADRA1D (0.38) | ADRA1D | |
| SCHEMBL26629189 | 0.73 | ADRA1D (0.41) | ADRA1D | |
| SCHEMBL26165274 | 0.72 | POLB (0.33) | ADRA1D | |
| SCHEMBL26629171 | 0.70 | ADRA1D (0.33) | ADRA1D | |
| SCHEMBL30635687 | 0.68 | — | — | |
| SCHEMBL2487056 | 0.67 | CYP2C19 (0.41) | SMN1; SMN2 | |
| SCHEMBL27688660 | 0.66 | ADRA1D (0.42) | ADRA1DSMN1; SMN2 | |
| SCHEMBL27688823 | 0.63 | ALOX5 (0.42) | ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |