Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635671 | 0.90 | HDAC1 (0.45) | TYK2LRRK2JAK1JAK2ALK | |
| SCHEMBL25204632 | 0.86 | LRRK2 (0.39) | TYK2LRRK2MAP3K12ALK | |
| SCHEMBL26629481 | 0.85 | PTK2 (0.40) | LRRK2JAK1PTK2FLT4ALK | |
| SCHEMBL25198593 | 0.85 | PTK2 (0.40) | LRRK2JAK1PTK2FLT4ALK | |
| SCHEMBL26629226 | 0.82 | MAP3K12 (0.37) | TYK2LRRK2JAK1MAP3K12PTK2 | |
| SCHEMBL26629380 | 0.82 | ALK (0.40) | TYK2LRRK2JAK1PTK2FLT4 | |
| SCHEMBL25235038 | 0.79 | LRRK2 (0.38) | TYK2LRRK2MAP3K12 | |
| SCHEMBL25207066 | 0.79 | LRRK2 (0.38) | TYK2LRRK2MAP3K12 | |
| SCHEMBL30412481 | 0.79 | LRRK2 (0.38) | TYK2LRRK2MAP3K12 | |
| SCHEMBL25202448 | 0.79 | LRRK2 (0.43) | LRRK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |