Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 2/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
| ▸ | DRD5 | P21918 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634713 | 0.85 | MAOB (1.00) | MAOAMAOBSLC6A4CHRNA7DRD1 | |
| SCHEMBL5525085 | 0.85 | MAOB (1.00) | MAOAMAOBSLC6A4CHRNA7DRD1 | |
| Hydrochloric Acid SCHEMBL20854708 | 0.83 | MAOB (0.96) | MAOAMAOBSLC6A4CHRNA7DRD1 | |
| Hydrochloric Acid SCHEMBL30634715 | 0.83 | MAOB (0.96) | MAOAMAOBSLC6A4CHRNA7DRD1 | |
| SCHEMBL24394226 | 0.82 | MAOA (0.65) | MAOAMAOBSLC6A4CHRNA7MAP4K1 | |
| SCHEMBL29843393 | 0.79 | MAOA (0.60) | MAOAMAOBSLC6A4CHRNA7MAP4K1 | |
| SCHEMBL24420537 | 0.79 | MAOA (0.50) | MAOAMAOBSLC6A4CHRNA7MAP4K1 | |
| SCHEMBL24746023 | 0.79 | MAOA (0.80) | MAOAMAOBSLC6A4CHRNA7MAP4K1 | |
| SCHEMBL19815866 | 0.78 | MAPT (0.46) | MAOAMAOBSLC6A4CHRNA7MEN1 | |
| SCHEMBL20939758 | 0.78 | MAOB (0.77) | MAOAMAOBSLC6A4CHRNA7DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339896-A1 | HPK1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339896-A1 | HPK1 INHIBITORS AND USES THEREOF | HIPK1, MAPKAPK5, MLKL | MAOA 4479/4885MAOB 4521/4885SLC6A4 3814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.