Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402907 | 0.84 | POLB (0.61) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL13402898 | 0.84 | ALDH1A1 (0.49) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL22289272 | 0.83 | HPGD (0.49) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL2652440 | 0.80 | HPGD (0.44) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL12999968 | 0.80 | L3MBTL1 (0.71) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL3494577 | 0.80 | KMT2A (0.49) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL13402915 | 0.79 | CYP2D6 (0.48) | LMNAALDH1A1HPGDTSHRHDAC4 | |
| SCHEMBL22289268 | 0.78 | HPGD (0.63) | LMNAALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL3496498 | 0.78 | KMT2A (0.54) | LMNAALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL30954338 | 0.78 | L3MBTL1 (0.71) | L3MBTL1LMNAALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |