Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651717 | 0.77 | GCGR (0.61) | HRH3GCGRHDAC1EPHX2 | |
| SCHEMBL9072674 | 0.77 | HDAC1 (0.57) | HRH3CA1CA2GCGRHDAC1 | |
| SCHEMBL2663270 | 0.76 | HRH3 (0.50) | HRH3CA1CA2GCGRHDAC1 | |
| SCHEMBL2650729 | 0.75 | GCGR (0.54) | HRH3GCGRHDAC1LMNACXCR4 | |
| SCHEMBL2663237 | 0.73 | HDAC1 (0.52) | HRH3CA1CA2GCGRHDAC1 | |
| SCHEMBL2663087 | 0.73 | HRH3 (0.47) | HRH3CA1CA2GCGRHDAC1 | |
| SCHEMBL2663474 | 0.72 | GCGR (0.53) | HRH3GCGRHDAC1CXCR4EPHX2 | |
| SCHEMBL12301977 | 0.72 | LMNA (0.70) | LMNAEPHX2 | |
| SCHEMBL9072917 | 0.72 | GCGR (0.56) | HRH3GCGRHDAC1LMNACXCR4 | |
| SCHEMBL9072855 | 0.70 | GCGR (0.49) | HRH3GCGREPHX2KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |