Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.41 |
| ▸ | GIPR | P48546 | 6/20 | 0.41 |
| ▸ | STAT3 | P40763 | 11/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663352 | 0.84 | STAT3 (0.54) | GCGRGIPRSTAT3HDAC1HDAC6 | |
| SCHEMBL2663309 | 0.83 | STAT3 (0.46) | GCGRGIPRSTAT3HDAC1HDAC6 | |
| SCHEMBL2663367 | 0.82 | STAT3 (0.47) | GCGRGIPRSTAT3HDAC1HDAC6 | |
| SCHEMBL2663189 | 0.81 | GCGR (0.57) | GCGRGIPRSTAT3 | |
| SCHEMBL2663582 | 0.80 | STAT3 (0.45) | GCGRGIPRSTAT3 | |
| SCHEMBL2663354 | 0.80 | GCGR (0.50) | GCGRGIPRSTAT3 | |
| SCHEMBL2663358 | 0.79 | STAT3 (0.55) | GCGRGIPRSTAT3HDAC1HDAC6 | |
| SCHEMBL4095377 | 0.79 | GCGR (0.53) | GCGRGIPRSTAT3 | |
| SCHEMBL2663379 | 0.78 | STAT3 (0.45) | GCGRGIPRSTAT3 | |
| SCHEMBL2663356 | 0.78 | HDAC6 (0.52) | GCGRGIPRSTAT3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |