Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 9/20 | 0.45 |
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | GIPR | P48546 | 5/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | STAT5B | P51692 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663321 | 0.87 | STAT3 (0.49) | STAT3GCGRGIPRSTAT1STAT5B | |
| SCHEMBL2663379 | 0.87 | STAT3 (0.45) | STAT3GCGRGIPROPRM1OPRK1 | |
| SCHEMBL2663367 | 0.86 | STAT3 (0.47) | STAT3GCGRGIPRLTB4R2OPRM1 | |
| SCHEMBL2663358 | 0.86 | STAT3 (0.55) | STAT3GCGRGIPROPRM1OPRK1 | |
| SCHEMBL2663352 | 0.84 | STAT3 (0.54) | STAT3GCGRGIPROPRM1OPRK1 | |
| SCHEMBL2663309 | 0.83 | STAT3 (0.46) | STAT3GCGRGIPR | |
| SCHEMBL2663183 | 0.80 | GCGR (0.41) | STAT3GCGRGIPR | |
| SCHEMBL9072944 | 0.79 | GCGR (0.41) | STAT3GCGRGIPR | |
| SCHEMBL2663354 | 0.79 | GCGR (0.50) | STAT3GCGRGIPR | |
| SCHEMBL2663189 | 0.78 | GCGR (0.57) | STAT3GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |