Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | GIPR | P48546 | 2/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091439 | 0.78 | GCGR (0.51) | NR1H4EPHX2MEN1KMT2AGCGR | |
| SCHEMBL2663513 | 0.75 | GCGR (0.44) | NR1H4MEN1KMT2AGCGRGIPR | |
| SCHEMBL2663126 | 0.73 | GCGR (0.47) | NR1H4MEN1KMT2AGCGRGIPR | |
| SCHEMBL2663340 | 0.73 | NR1H4 (0.39) | NR1H4MEN1KMT2APTGESALOX5 | |
| SCHEMBL9072920 | 0.73 | MAPT (0.47) | NR1H4MEN1KMT2AGCGRGIPR | |
| SCHEMBL9072679 | 0.73 | OPRK1 (0.38) | MEN1KMT2AGCGRGIPRGLP1R | |
| SCHEMBL9072801 | 0.72 | GCGR (0.47) | NR1H4MEN1KMT2AGCGRGIPR | |
| SCHEMBL2663372 | 0.72 | GCGR (0.48) | MEN1KMT2AGCGRGIPRGLP1R | |
| SCHEMBL2663220 | 0.72 | KMT2A (0.53) | MEN1KMT2AGCGRGIPRGLP1R | |
| SCHEMBL2663134 | 0.72 | RAB9A (0.50) | MEN1KMT2AGCGRGIPRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |