SCHEMBL2663291

SCHEMBL2663291

CC(Oc1ccc(Cl)cc1)C(=O)N(Cc1ccc(C(=O)N/C(N=N)=N/N)cc1)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GCGR P47871 7/20 0.45
GIPR P48546 6/20 0.45
STAT3 P40763 7/20 0.42
GHSR Q92847 3/20 0.40
IDO1 P14902 1/20 0.39
STAT1 P42224 1/20 0.38
STAT5B P51692 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9072819 0.93 GCGR (0.47) GCGRGIPRSTAT3GHSR
SCHEMBL2663565 0.90 GCGR (0.54) GCGRGIPRSTAT3
SCHEMBL9072688 0.89 GCGR (0.43) GCGRGIPRSTAT3GHSRIDO1
SCHEMBL2663352 0.81 STAT3 (0.54) GCGRGIPRSTAT3
SCHEMBL2663375 0.80 STAT3 (0.48) GCGRGIPRSTAT3
SCHEMBL2663335 0.80 GCGR (0.42) GCGRGIPRGHSR
SCHEMBL4096091 0.79 GCGR (0.53) GCGRGIPRSTAT3GHSR
SCHEMBL2663162 0.78 GCGR (0.58) GCGRGIPRSTAT3
SCHEMBL2663329 0.78 GCGR (0.40) GCGRGIPR
SCHEMBL2663189 0.77 GCGR (0.57) GCGRGIPRSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000069810-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-11-23 WO disclosed