SCHEMBL2663565

SCHEMBL2663565

CC(Oc1ccc(OC(F)(F)F)cc1)C(=O)N(Cc1ccc(C(=O)N/C(N=N)=N/N)cc1)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 10/20 0.54
GIPR P48546 9/20 0.43
STAT3 P40763 9/20 0.41
GLP1R P43220 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2663291 0.90 GCGR (0.45) GCGRGIPRSTAT3
SCHEMBL2663162 0.89 GCGR (0.58) GCGRGIPRSTAT3GLP1R
SCHEMBL2663329 0.88 GCGR (0.40) GCGRGIPRGLP1R
SCHEMBL2663189 0.87 GCGR (0.57) GCGRGIPRSTAT3GLP1R
SCHEMBL9072819 0.86 GCGR (0.47) GCGRGIPRSTAT3
SCHEMBL2663354 0.81 GCGR (0.50) GCGRGIPRSTAT3
SCHEMBL4087079 0.80 GCGR (0.56) GCGRGIPRGLP1R
SCHEMBL9072688 0.79 GCGR (0.43) GCGRGIPRSTAT3
SCHEMBL2663352 0.79 STAT3 (0.54) GCGRGIPRSTAT3
SCHEMBL2663375 0.78 STAT3 (0.48) GCGRGIPRSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000069810-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-11-23 WO disclosed